Showing posts with label microbiome. Show all posts
Showing posts with label microbiome. Show all posts

17 June 2016

Seven Reasons a Brain Injury can Destroy Your Gut!


Seven Reasons a Brain Injury Can Destroy Your Gut

According to the CDC, incidence of hospital visits for traumatic brain injury have increased over the past decade.  It is one of the leading causes of disability world-wide.  You may know that the gut and brain are intricately connected but did you know that many people who experience brain trauma often experience resulting gut issues?   The gut problems come from alternations in the gut-brain axis or the communication network between our intestines and our cerebral matter.   When this delicate network is disrupted, it may result in dramatic gastrointestinal dysfunction, chronic pain or even disability.
According to Dr. Kharrazian, there are seven key ways in which traumatic brain injury can alter GI function, each of which may contribute to your chronic gastrointestinal disorders.
  1. Autonomic Dysregulation - this occurs when the autonomic nervous system no longer appropriately  controls things that should come automatically, like heart rate, breathing, and gut motility.   If the system becomes overactive to a sympathetic stimulus the result may trigger a chronic pain loop that is hard to control, leading to abdominal pain.
  2. Disorders of visceral sensing and processing - Visceral sensing is the gut's way of telling the brain what is going on.   Sensations in the gut such as temperature, pH, contractility communicate with the brain to notify the body what is happening in the digestive system.  Disruption of these sensing circuits is one of the main factors implicated in irritable bowel disorders (IBS).  Brain injury often contributes to a broken communication network between gut and brain.
  3. Increase in intestinal permeability (leaky gut) -  After brain  injury the tight junctions that connect the cells that line your gut often become dysfunctional and allow large molecules to enter from the digestive tract into the blood stream.  Normally these tight junctions are protecting you from the large molecules, such as undigested food particles, bacterial parts or other luminal contacts that could cross over into the blood stream.  We know that the increase in intestinal permeability is a key factor in the development of autoimmune diseases, from Hashimoto's thyroiditis to multiple sclerosis.
  4. Compromise of intestinal mucosa - Very commonly after brain injury, there is a compromise in the health of the mucosal lining.  We see this in patients in the Intensive Care Unit (ICU) as well... anytime the body is under massive stress, there is a tendency for the mucosa that lines the gut to atrophy and die.  The changes we see are often immediate and occur within minutes after brain injury, severe trauma or infection.
  5. Breakdown of the blood-brain barrier (BBB) - The BBB, as it is affectionately known, protects your delicate gray matter from outside chemicals and inflammatory agents that may cause problems if allowed to enter.  After a brain injury, this barrier is often compromised, allowing massive inflammatory triggers inside the brain where they do not belong.
  6. Brain Immune Dysfunction  - The Central Nervous System (CNS) controls much of the immune system and the production of inflammatory signaling molecules, like cytokines.  If there is an injury to the signaling mechanism it may contribute to either over-activation or under-activation of the immune system  This can lead to either immune compromise or autoimmune disease, where the body attacks itself.
  7. Impaired gut motility - Sadly we see this as a factor in many disorders such as intestinal dysbiosis and SIBO (small intestinal bacterial overgrowth).   The impairment in smooth muscle contractility of the gut mucosa leads to dysmotility. This dysmotility leads stagnation  and alteration in bowel function and even malabsorption.  Ultimately patients may have very severe symptoms related to this problem of abnormal peristalsis in the gut.
Can see how these many mechanisms of action on the gut after brain injury may contribute to chronic pain and dysfunction, not only in the gut but the immune system as well?  Here's some simple things you can do to ensure you will maintain a healthy gut for life!

So What Can I Do to Maintain a Healthy Gut?

  1. Eat a variety of colorful organic and local produce
  2. Avoid genetically modified foods and glyphosate which contribute to a leaky gut
  3. Take a daily multi-strain probiotic to support your microbiome and immune system
  4. Eat prebiotic-rich fruits and vegetables to feed your healthy gut bugs
  5. Protect your noggin!  Wear a helmet if you are skiing, biking or doing any activity that involves risk of head trauma
  6. Try Restore, my favorite new product to restore gut health and heal tight junctions.  Call Amy at #303-993-7910 if you would like more info....

Although we cannot predict or even prevent a head injury, it's important to realize that if it does happen to you, your gut function may be affected.   Start NOW to take steps to develop a healthy gut microbiome in the meantime!



16 May 2014

6 Signs that SIBO might be the root cause of your IBS

Photo courtesy of www.freedigitalphotos.net

Studies show that over 50% of patients diagnosed with IBS actually have an underlying imbalance called SIBO, or small intestinal bacterial overgrowth. The majority of our gut bacteria should be in the colon. When the bacteria migrate backwards into the small bowel or when there is low stomach acid or poor pancreatic enzyme production, bacteria in the small bowel can overgrow and cause symptoms, such as diarrhea, gas, or bloating.

Six signs you might have SIBO

  1. You notice that fiber worsens your constipation
  2. You notice an improvement in IBS symptoms when taking antibiotics
  3. You feel more gas and bloating when you take probiotics that contain prebiotics
  4. You are celiac or gluten intolerant and do not have 100% resolution of symptoms on a gluten-free diet
  5. You develop chronic symptoms of gas, bloating, constipation or diarrhea after taking pain medications, like opiates.
  6. Your blood work shows chronically low iron or ferratin with no known cause

Top 6 Symptoms of SIBO

  1. Abdominal bloating and distention
  2. Constipation 
  3. Diarrhea
  4. Abdominal pain or discomfort
  5.  Acid reflux or heartburn
  6. Excessive gas or belching

How do I know this isn’t just leaky gut?


While SIBO usually manifests with local GI symptoms, a leaky gut will manifest with systemic complaints that affect the immune system. Keep in mind that is is not uncommon to have both SIBO and leaky gut simultaneously. And very often if you have SIBO for a long period of time, you will develop a leaky gut.

Here are some systemic signs of a leaky gut:

  • Multiple food sensitivities
  • Skin rashes, acne or rosacea
  • Respiratory symptoms, like asthma
  • Allergic symptoms or increase in seasonal allergies
  • Fatigue
  • Brain fog or poor concentration, especially after meals
  • Any autoimmune disease
  • Joint pain or arthritis
  • Headaches or migraines
Remember SIBO can cause leaky gut syndrome but not everyone with SIBO has leaky gut. About half of the patients diagnosed with SIBO will also have leaky gut. Most of the time if SIBO is treated, leaky gut will heal itself!

10 conditions that may predispose you to have SIBO

  1. Hypochlorhydria (low stomach acid)
  2. Pancreatic insufficiency
  3. Decreased motility in small intestine
  4. Bowel obstruction
  5. Diverticula 
  6. Surgical bowel resection or bariatric surgery 
  7. Food poisoning (Post infectious IBS)
  8. Nerve damage that affects the GI tract
  9. Drugs, like opiates 
  10. Any disease that slows motility (diabetes, hypothyroid)

Other disorders that may be associated with SIBO


  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Scleroderma
  • Hashimoto’s thyroiditis
  • Rosacea
  • Restless leg syndrome
  • Pancreatic insufficiency
  • Liver disease
  • Diabetes
  • Crohn’s disease
  • Celiac disease
  • Fibromyalgia
  • Kidney failure
  • Liver disease
  • Diverticulosis


How to Diagnose SIBO


Ask your doctor to order the Lactulose Breath Test (preferred over glucose as it will test the entire small bowel vs. just duodenum). You may also need to check a comprehensive stool analysis and urinary organic acids, which may point in the direction of other dysbiosis but are not directly assessing small bowel bacterial overgrowth

How do we treat SIBO?

1. Diet options
2. Antibiotics
  • Xifaxan
3. Dr. Jill’s favorite antimicrobial herbs

Treating SIBO successfully is not always easy and may involve major dietary changes and medication or herbal treatment for an extended period of time. However, getting the balance of your gut microbes healthy will likely prove to be the most important step in regaining your health and vitality! I know it was in my case… if you haven't read My Story, read more here.

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