Showing posts with label gut microbes. Show all posts
Showing posts with label gut microbes. Show all posts

17 June 2016

Seven Reasons a Brain Injury can Destroy Your Gut!


Seven Reasons a Brain Injury Can Destroy Your Gut

According to the CDC, incidence of hospital visits for traumatic brain injury have increased over the past decade.  It is one of the leading causes of disability world-wide.  You may know that the gut and brain are intricately connected but did you know that many people who experience brain trauma often experience resulting gut issues?   The gut problems come from alternations in the gut-brain axis or the communication network between our intestines and our cerebral matter.   When this delicate network is disrupted, it may result in dramatic gastrointestinal dysfunction, chronic pain or even disability.
According to Dr. Kharrazian, there are seven key ways in which traumatic brain injury can alter GI function, each of which may contribute to your chronic gastrointestinal disorders.
  1. Autonomic Dysregulation - this occurs when the autonomic nervous system no longer appropriately  controls things that should come automatically, like heart rate, breathing, and gut motility.   If the system becomes overactive to a sympathetic stimulus the result may trigger a chronic pain loop that is hard to control, leading to abdominal pain.
  2. Disorders of visceral sensing and processing - Visceral sensing is the gut's way of telling the brain what is going on.   Sensations in the gut such as temperature, pH, contractility communicate with the brain to notify the body what is happening in the digestive system.  Disruption of these sensing circuits is one of the main factors implicated in irritable bowel disorders (IBS).  Brain injury often contributes to a broken communication network between gut and brain.
  3. Increase in intestinal permeability (leaky gut) -  After brain  injury the tight junctions that connect the cells that line your gut often become dysfunctional and allow large molecules to enter from the digestive tract into the blood stream.  Normally these tight junctions are protecting you from the large molecules, such as undigested food particles, bacterial parts or other luminal contacts that could cross over into the blood stream.  We know that the increase in intestinal permeability is a key factor in the development of autoimmune diseases, from Hashimoto's thyroiditis to multiple sclerosis.
  4. Compromise of intestinal mucosa - Very commonly after brain injury, there is a compromise in the health of the mucosal lining.  We see this in patients in the Intensive Care Unit (ICU) as well... anytime the body is under massive stress, there is a tendency for the mucosa that lines the gut to atrophy and die.  The changes we see are often immediate and occur within minutes after brain injury, severe trauma or infection.
  5. Breakdown of the blood-brain barrier (BBB) - The BBB, as it is affectionately known, protects your delicate gray matter from outside chemicals and inflammatory agents that may cause problems if allowed to enter.  After a brain injury, this barrier is often compromised, allowing massive inflammatory triggers inside the brain where they do not belong.
  6. Brain Immune Dysfunction  - The Central Nervous System (CNS) controls much of the immune system and the production of inflammatory signaling molecules, like cytokines.  If there is an injury to the signaling mechanism it may contribute to either over-activation or under-activation of the immune system  This can lead to either immune compromise or autoimmune disease, where the body attacks itself.
  7. Impaired gut motility - Sadly we see this as a factor in many disorders such as intestinal dysbiosis and SIBO (small intestinal bacterial overgrowth).   The impairment in smooth muscle contractility of the gut mucosa leads to dysmotility. This dysmotility leads stagnation  and alteration in bowel function and even malabsorption.  Ultimately patients may have very severe symptoms related to this problem of abnormal peristalsis in the gut.
Can see how these many mechanisms of action on the gut after brain injury may contribute to chronic pain and dysfunction, not only in the gut but the immune system as well?  Here's some simple things you can do to ensure you will maintain a healthy gut for life!

So What Can I Do to Maintain a Healthy Gut?

  1. Eat a variety of colorful organic and local produce
  2. Avoid genetically modified foods and glyphosate which contribute to a leaky gut
  3. Take a daily multi-strain probiotic to support your microbiome and immune system
  4. Eat prebiotic-rich fruits and vegetables to feed your healthy gut bugs
  5. Protect your noggin!  Wear a helmet if you are skiing, biking or doing any activity that involves risk of head trauma
  6. Try Restore, my favorite new product to restore gut health and heal tight junctions.  Call Amy at #303-993-7910 if you would like more info....

Although we cannot predict or even prevent a head injury, it's important to realize that if it does happen to you, your gut function may be affected.   Start NOW to take steps to develop a healthy gut microbiome in the meantime!



31 August 2014

The Hidden Epidemic... Is Yeast Overgrowth Destroying Your Health?

Did you know your gut microbes could be dramatically affecting your health?

Hey guys! ...this is not just for women.  Men, too, commonly suffer from intestinal yeast overgrowth or fungal dysbiosis!

Every day we see new research on the effects of unhealthy gut organisms on the brain, the thyroid gland, the nervous system, the immune system, and the heart and vascular system.  In functional medicine, this is one reason we focus so intently on helping our patients heal their gut and thrive.  Without a healthy bacterial population in the colon, it’s nearly impossible to experience the optimal health we all desire.
Many people are unknowingly fighting a battle against a single-cell fungus in the gut.  Its name is Candida Albicans, although in recent years there has been an increase in non-albicans species of yeast.  Candida is a normal organism that is part of our skin flora, intestinal microbes, and for women, vaginal flora.  Men, this doesn't mean you can't harbor yeast as well!   This seemingly benign player can become hostile if the environment is right.  High intake of refined carbohydrates and sugar, frequent antibiotic or prednisone use, hormones and birth control pills and other medications give the yeast an advantage over the normal protective bugs, like lactobacillus, so that it flourishes.  It has the ability to take over and becomes invasive leading to a host of unwanted symptoms.  Sadly, many conventional physicians do not recognize that the gut can be a reservoir of these fungal organisms.   If you have ever experienced vaginal yeast infections, rectal irritation, white coating on your tongue called thrush, or any fungal skin or nail infections, like onychomycosis, you may also have a large number of these buggers living in your gastrointestinal tract.

I crave sweets and carbs all the time…

One of the most important things that I notice with patients who have fungal dysbiosis is the feeling of being tired and “run down” all the time with intense cravings for sugar or carbohydrates. Many patients don’t believe me when I tell them that if their gut is healthy, they will get to the point of having no food cravings at all!  It’s really true!  And if you are still experiencing intense, uncontrollable cravings, binge eating, or other issues in a love-hate relationship with sugar and refined carbohydrates, you can bet there is a problem with your gut microbes!

Take this quiz to find out if YOU have a problem!

These are common symptoms that may occur with yeast overgrowth in the gut.  Keep in mind, these are not specific to yeast alone, but if you experience them on a regular basis you are likely to have a real problem with fungal dysbiosis, or yeast overgrowth.
 Give yourself 1 point for every one of these symptoms you experience regularly:
  • Weight gain
  • Difficulty losing weight
  • Premenstrual symptoms
  • Fatigue
  • Muscle pain/fibromyalgia
  • Poor focus/concentration
  • Brain fog
  • Irritable
  • Depression
  • Anxiety
  • Headaches or migraines
  • Cravings for sugar or carbohydrates
  • Drowsy after meals
  • Constipation
  • Diarrhea
  • Gas and bloating
  • Rectal itching
  • Vaginal discomfort or burning
  • Low libido
  • Joint pain
  • Crying spells
  • Dizziness or light-headedness
  • Sinus pressure/congestion
  • Trouble sleeping
  • Halitosis (bad breath)
  • Body odor
  • Frequent sore throat
  • Coughing/wheezing/shortness of breath
Scoring
  • > 8 – You may have intestinal dysbiosis
  • > 14 – It is likely you have an issue with intestinal dysbiosis, which could include yeast overgrowth
  • > 20 – It is almost certain that you have fungal dysbiosis or yeast overgrowth

Fungal Dysbiosis and Leaky Gut Syndrome

If yeast becomes dominant in the gut, it may take over and overwhelm the good bacteria.  This is called Fungal Dysbiosis.  The situation becomes dire when yeast or abnormal gut microbes proliferate and dysbiosis occurs.  The problems start when yeast changes from a benign one cell organism to the more invasive hyphe form.  These forms can secrete enzymes, like proteases and phosopholipases that break down cell membranes and contribute to intestinal permeability or “leaky gut”.  As the gut becomes more permeable, toxic metabolites, such as acetaldehyde, leak into the blood stream and cause symptoms such as brain fog, fatigue, or depression.  Did you know that this chemical yeast produces can make you feel hungover?  Alcohol, when metabolized by the liver, also produces acetaldehyde which causes that "hangover" feeling.  The yeast bugs also drive cravings for the very foods that allow them to survive –sugar, refined carbohydrates and sometimes fermented foods or alcohol.  I’m always amazed by the number of people who were struggle with alcohol craving or addiction that have yeast overgrowth in their gut.  In addition to the toxic materials that leak into the blood stream, partially digested food may also leak through the lining of the gut and create food sensitivities.  Many people with chronic yeast overgrowth will experience sensitivities to common foods, like gluten, dairy, sugar, corn, and soy and may even experience improvement in symptoms when they go on an elimination diet.  Yeast also produces more than one-hundred other toxins that may leak into the blood stream and affect thyroid and hormone function, brain function and even neurotransmitter production.

Fungal Dysbiosis and the Connection with Autoimmune Diseases

This invasion and consequent problem of a leaky gut may also trigger the immune system to become confused in a process called “molecular mimicry” when the bacteria or yeast in the gut or cross over where they don’t belong into the blood stream and trigger creation of antibodies by the immune system.  These antibodies may cross-react to joint tissue, skin, thyroid, or even brain and create autoimmune diseases.  It is very common to see some of the following autoimmune conditions occur in someone with fungal dysbiosis:
  • Psoriasis
  • Rheumatoid arthritis
  • Hashimoto’s thyroiditis
  • Crohn’s disease
  • Ulcerative Colitis
  • Celiac Disease
  • Meniere’s disease
  • Raynaud’s disease
  • Lupus

 So What Causese Fungal Dysbiois?

Here are some of the most common factors that upset the balance of gut microbes and contribute to yeast overgrowth or fungal dysbiosis
  • Chronic stress, which impacts your immune system, also contributes to yeast overgrowth
  • Diabetes (due to abnormal blood sugar)
  • Pregnancy (due to change in hormone levels)
  • Eating too much sugar and too many grains. Sugar is the main fuel for yeast.
  • Taking antibiotics, which kill both your good and bad bacteria.
  • Exposure to environmental toxins, which can lower your immune system’s ability to keep yeast in check.  Mercury is especially problematic with yeast overgrowth
  • Taking other medications, such as birth control pills and steroids, which are both known to increase yeast

How Does My Doctor Diagnose Fungal Dysbiosis?

Well, the first step is finding a functional medicine trained physician or naturopath who understands the importance of having a healthy gut microbiome.  There are many physicians who understand vaginal yeast infections or the more severe systemic candidiasis, where candida enters the blood stream and can be life threatening but ignore the possibility that you could have too many yeast bugs living in your gut.  Even when we are looking for a problem it can often be hard to detect.  I commonly use a combination of clinical history and symptoms and the following lab tests:
  1. Serum Candida antibiodies (IgG, IgM, IgA)
  2. Organic Acids in urine, such as Arabinose
  3. Comprehensive Digestive Stool analysis for candida culture and sensitivity
By combining a patient’s symptoms with the testing above, it becomes relatively easy to determine if a patient has fungal dysbiosis or not.  Other red flags are someone with  inflammatory bowel disorder or other bacterial dysbiosis, such as SIBO (small intestinal bacterial overgrowth) as the two can co-exsist.

So Tell Me How to Get Rid of it!

1. DIET

The most important starting point is diet.  In fact, I frequently tell patients that no amount of anti-fungal drugs or herbal medications can overcome a high sugar, high carbohydrate diet.  In order to eradicate the yeast, one must do the following:
  1. Eat a diversified, whole foods (in as natural and fresh a state as possible) diet, emphasizing non-starchy vegetables, proteins, like fish, organic chicken, turkey, lamb, wild game and organic grass-fed beef.  Healthy oils, like coconut, grape seed and olive are also essential. Include pastured ghee or butter as well for a rich source of Vitamin K and other fat-soluble vitamins
  2. Chose organic, free-range meat and be sure they do not contain added growth hormones or antibiotics.  I advise all patients to avoid cow’s dairy due to lactose content, which is a sugar that yeast likes.
  3. Avoid all foods that feed the yeast!  That would include all forms of sugar (honey, molasses, maple syrup, agave, xylitol, and artificial sweeteners, like aspartame, splenda)
  4. Avoid all dried fruits and fruit juices.  Stevia may be used to sweeten teas and beverages.
  5. You may need to eliminate fruit in the beginning or at least stick to no more than one serving of low-glycemic fruit per day – best bets are berries, green apples, or citrus.
  6. Eliminate any allergenic foods – these commonly include gluten, dairy, egg, soy, corn, and cane sugar
  7. You should also eliminate the following: alcohol; vinegar (and anything containing vinegar, like salad dressing and sauces); all bread (which contains yeast); high starchy vegetables, like carrots, potatoes and beets; peanuts and corn (due to high mold content); mushrooms (fungus); and aged or moldy foods, like blue cheese.
  8. Drink plenty of purified water daily.  If you are feeling dizzy, add some electrolytes (ElectroMix or Elyte Sport) to your morning water.
  9. Get some form of daily exercise (walking, hiking, yoga, bicycling). Pick an activity you enjoy and try to get in 30-40min every day.
  10. Make time for rest and relaxation.  Epson salt baths can be especially helpful for the yeast die-off symptoms.  Use 2-3 cups of salt in warm bath and soak 20min.

2. AVOID ANTIBIOTICS

3. DECREASE STRESSORS

4. IDENTIFY AND ELIMINATE FOOD ALLERGIES

5. TAKE A PROBIOTIC!  (my favorite is Klaire Labs Detox Support, which you can order here)

6. TREAT ANY DIGESTIVE IMBALANCES (like insufficient pancreatic enzyme production or low stomach acid)

7. MEDICATIONS

  • Fluconazole
  • Itraconazole
  • Nystatin
  • Compounded Oral amphotericin B

8. HERBAL REMEDIES

  • Caprylic Acid
  • Undecylenic acid
  • Berberine
  • Garlic (Allicin)
  • Oil of Oregano
  • Olive Leaf Extract
  • Pau D-Arco
  • Grape Seed Extract

9. OTHER ESSENTIAL NUTRIENTS

  • Vitamin D
  • Vitamin A
  • Biotin
  • Essential Fatty acids
  • Probiotics
  • Pantethine
  • l-Glutamine
  • Coenzyme Q10
  • Magnesium

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21 August 2014

Why I'm a fan of Bulletproof Coffee...

Smell that coffee... mmmm!

I wake up around 4:50 am to the sound of my automatic Cuisinart coffee maker grinding fresh Upgraded coffee beans into the filter for a delicious fresh brew.   There is nothing better than rubbing your eyes, rolling out of bed, and padding across the cool hardwood to the kitchen as the amazing aroma of fresh brewed coffee fills the air.  Those pre-dawn hours are my absolute most productive and favorite time of day!
I thought I'd share a few of the things I've learned along the way for how to maximize the health benefits of your coffee.  I'm proud to say that I enjoy Upgraded beans because I can literally feel the difference in my mental clarity when I drink it instead of non-organic, pesticide laden, mycotoxin filled alternatives like Starbucks (oh, yes you heard me, right!).  While many of you may not be environmentally sensitive to chemicals like I am, you should really give it a try as the brain power you get from a cup of the really pure stuff will blow your mind!

Shop UpgradedSelf.com

Travel Tips?

And when I travel I take along Upgraded coffee cartridges, empty one into a 16oz cup, and pour boiling hot water over it for an instant "french press" brew.  After letting it steep for 2-3 minutes, I pour the brewed coffee out into a new cup careful to leave the grinds in the old one and viola!... delicious amazing, mycotoxin-free coffee anytime, anywhere.  Last time I was in an airport asking for a large glass of hot water, the man on the barstool next to me asked if I was performing a science experiment!?  Haha!  I just smiled and said, "yes".   It didn't help that I dug in my purse and pulled out my travel vial of SweetLeaf English toffee stevia drops and a few shakes from a purse-size organic cinnamon powder which I also carry with me at all times.  I've become accustomed to the funny looks I get and I really don't even care ;-)

Upgraded Brain Octane Oil

My not-so-dirty little secret for amazing brain power at 5am!

Let me share with you my secret for 5am productivity like you've never experienced before.  After brewing a pot of this delicious black velvet, I add in a few little "brain helpers".  I was having coffee with a friend today and telling her about it so I thought I would write a blog and share with you, too.   You can get the Dave Asprey's original Bulletproof Coffee Recipe here but here is my version:



Dr. Jill's 5am Brain-Power Brew

  • Pour 1/4 to 1/2 cup full-fat organic unsweetened coconut milk into your favorite mug
  • Add fresh-brewed, hot Bulletproof coffee leaving 1/4 inch from top of mug
  • Add 5 drops of Sweet Leaf English Toffee or Vanilla stevia (if you like a carmel or vanilla "latte" flavor)
  • Add 1 teaspoon of Upgraded Brain Octane Oil 
  • Generously sprinkle organic cinnamon powder into your coffee
  • Add 1 scoop of Upgraded Collagen Powder and stir!  (you won't believe what the collagen will do for you joints and skin... truly amazing!)
  • If you like it frothy, you can whip it all up in a blender with heat-safe blades,  but I just drink mine as is.
  • If I'm feeling a little more adventurous, I'll might add a tablespoon of toasted organic shredded coconut in, too
Upgraded Collagen

A few cool facts about coffee

  1. Chronic coffee consumption may alter your gut microbes and is associated with lower body weight and lower percent body fat.
  2. This article discusses benefits of polyphenols, especially from coffee and cocoa, on your gut microbiome.
  3. The bioactive components in coffee may have synergistic effects on brain cognition.
  4. In this study, coffee decreased boredom and fatigue associated with repetitive tasks.
  5. Caffeine intake associated with improved working memory in middle aged males.
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